Herbs-partitioned moxibustion alleviates aberrant intestinal epithelial cell apoptosis by upregulating A20 expression in a mouse model of Crohn’s disease

Figure 5 Co-expression of A20/tumor necrosis factor receptor 1-associated death domain in the intestinal epithelium of mice across groups. A: Wild-type mice in normal control group; B: Wild-type mice in model control group; C: Wild-type mice in mesalazine group; D: Wild-type mice in herbs-partitioned moxibustion group; E: A20^IEC-KO mice in normal control group; F: A20^IEC-KO mice in model control group; G: A20^IEC-KO mice in mesalazine group; H: A20^IEC-KO mice in herbs-partitioned moxibustion group. Data are presented as the mean ± standard deviation (n = 10). Data were evaluated for statistical significance using one-way analysis of variance and are represented as follows: ^aP < 0.05, ^bP < 0.01 as compared to normal contro; ^cP < 0.05, ^dP < 0.01 as compared to model control; ^eP < 0.05, ^fP < 0.01 as compared to mesalazine; ^gP < 0.05, ^hP < 0.01 as compared to wild type. TRADD: Tumor necrosis factor receptor 1-associated death domain; WT: Wild type; NC: Normal control; MC: Model control; MESA: Mesalazine; HPM: Herbs-partitioned moxibustion.