Immune response pattern varies with the natural history of chronic hepatitis B

Figure 2 Phenotypes of NK cells in different clinical phases. A: Frequency of CD56^bright and CD56^dim NK cells expressing the activating receptor NKp46; B: Frequency of CD56^bright and CD56^dim NK cells expressing the activating receptor NKp44; C: Frequency of CD56^bright and CD56^dim NK cells expressing the activating receptor NKp30; D: Frequency of CD56^bright and CD56^dim NK cells expressing the inhibitory receptor NKG2A; E: Frequency of CD56^bright and CD56^dim NK cells expressing the activating receptor NKG2D; F: Frequency of CD56^bright and CD56^dim NK cells expressing the activating marker CD69. NK: Natural killer; HD: Healthy honors; IT: Immune tolerant; IA: Immune active; IC: Inactive carrier; ENEG: Hepatitis B envelope antigen-negative hepatitis. All data are presented as mean ± SD, ^aP < 0.05, ^bP < 0.01, ^cP < 0.001.