Dual energy computed tomography for detection of metastatic lymph nodes in patients with hepatocellular carcinoma

Table 3 Cut-off values, area under the curve, sensitivity, and specificity of dual-energy computed tomography for metastatic vs non-metastatic lymph nodes in patients with hepatocellular carcinoma

Parameter		AUC	Cut-off value	Sensitivity, %	Specificity, %
Maximal short axis diameter(cm)		0.883	0.950	73.3	88.7
IC (mg/mL)	AP	0.697	9.845	68.6	72.0
	PP	0.902	18.060	81.9	82.4
	DP	0.755	16.005	73.6	76.9
NIC	AP	0.756	0.106	72.8	73.9
	PP	0.918	0.272	83.9	84.1
	DP	0.836	0.467	74.5	79.2
λHU	AP	0.755	0.582	73.8	75.6
	PP	0.889	1.098	81.8	84.1
	DP	0.836	1.077	78.1	79.0
Diameter + λHU (PP)		0.945	Combined diagnosis in parallel	86.2	89.8
Diameter + IC (PP)		0.884		84.5	83.0
Diameter + NIC (PP)		0.960		86.9	93.6

IC: Iodine concentration; NIC: Normalized iodine concentration; λ_HU: Slope of the spectral curve; AP: Arterial phase; PP: Portal phase; DP: Delayed phase.