Unconjugated bilirubin alleviates experimental ulcerative colitis by regulating intestinal barrier function and immune inflammation

Figure 6 UCB reduced production of proinflammatory cytokines in DSS induced colitis mice. A and B: Protein expression of TNF-α and IL-1β; C and D: mRNA transcript expression of TNF-α and IL-1β. Data are expressed as means ± SEM (n = 5). ^cP < 0.001 vs control group and ^fP < 0.001 vs DSS. UCB: Unconjugated bilirubin; DSS: Dextran sodium sulfate; TNF-α: Tumor necrosis factor α; IL-1β: Interleukin 1β; SEM: Standard error of the mean.