Functional role of long non-coding RNA CASC19/miR-140-5p/CEMIP axis in colorectal cancer progression in vitro

Figure 3 Role of cancer susceptibility 19 in the cell migration, invasion, and epithelial-mesenchymal transition in colorectal cancer cells. A: The migration abilities of SW480 and HCT-116 cells were analyzed by wound-healing assay after the cells were transfected with CASC19-p or siCASC19. Scale bars = 100 μm. B: The invasion abilities of SW480 and HCT-116 were determined by transwell assay after the cells were transfected with CASC19-p or siCASC19. Scale bars = 20 μm. C: The expression of vimentin, N-cadherin, and E-cadherin in HCT-116 and SW480 cells was detected by Western blot after transfection with CASC19-p or siCASC19. The grayscale value of protein was measured with Image J. Data are reported as the mean ± SD. ^aP < 0.05. CASC19: Cancer susceptibility 19.