Clinical characteristics of non-alcoholic fatty liver disease in Chinese adult hypopituitary patients

doi:10.3748/wjg.v25.i14.1741

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Retrospective Study

World J Gastroenterol. Apr 14, 2019; 25(14): 1741-1752
Published online Apr 14, 2019. doi: 10.3748/wjg.v25.i14.1741

Table 3 Liver function including liver enzymes, routine blood tests, and coagulation function tests in our patients

Index		NAFLD (-) (n = 23)	NAFLD (+)
Index		NAFLD (-) (n = 23)	NAFLD (n = 20)	Cirrhosis (n = 7)
Liver enzymes	ALT (U/L)	26.0 (20.0-41.0)	35.0 (27.3-81.8)	23.0 (19.0-59.0)
	ALB (g/L)	46.8 ± 3.5^a	47.7 ± 3.0^a	49.6 ± 4.6
	TBil (μmol/L)	8.7 (6.9-14.4)^b	12.3 (8.0-17.1)^a	13.2 (9.9-15.9)
	DBil (μmol/L)	2.6 (2.2-4.4)	3.4 (2.6-5.5)	4.4 (3.2-5.1)
	GGT (U/L)	23.0 (16.0-33.0)^a	52.0 (29.0-77.0)	52.0 (23.0-141.0)
	ALP (U/L)	77.0 (60.5-122.5)	82.0 (69.0-92.0)	71.0 (62.0-117.0)
	AST (U/L)	28.0 (22.5-38.5)	36.0 (26.0-55.0)	26.0 (20.0-59.0)
	TBA (μmol/L)	2.90 (1.35-3.25)	3.60 (2.30-7.00)	3.60 (1.30-9.10)
	LD (U/L)	233.9 ± 54.8	227.6 ± 41.4	215.3 ± 60.8
Routine blood tests	WBC (×10⁹/L)	6.53 ± 2.61^a	6.32 ± 1.71^a	4.02 ± 1.14
	NEUT# (×10⁹/L)	3.65 ± 1.90^b	3.44 ± 1.24^a	1.75 ± 0.30
	PLT (×10⁹/L)	250.5 ± 81.1^c	273.0 ± 90.1^c	91.1 ± 53.3
Coagulation function tests	PT (s)	12.11 ± 1.06^c	11.87 ± 1.01^c	15.43 ± 2.24
	PT% (%)	87.3 ± 8.8^c	94.3 ± 14.9^c	62.6 ± 12.1
	INR	1.05 ± 0.08^c	1.01 ± 0.10^c	1.33 ± 0.17
	FgB (g/L)	2.97 ± 0.78^b	3.09 ± 0.81^b	1.89 ± 0.59
	APTT (s)	31.35 (25.70-35.15)	28.45 (25.30-38.33)	33.50 (30.48-41.58)
	TT (s)	18.34 ± 0.97^b	17.82 ± 0.94^c	19.75 ± 1.08

^aP < 0.05 vs the cirrhosis group.

^bP < 0.01 vs the cirrhosis group.

^cP < 0.001 vs the cirrhosis group.

NAFLD: Non-alcoholic fatty liver disease; ALT: Alanine aminotransferase; ALB: Albumin; TBil: Total bilirubin; DBil: Direct bilirubin; GGT: γ-glutamyltransferase; ALP: Alkaline phosphatase; AST: Aspartate aminotransferase; TBA: Total bile acid; LD: Lactic dehydrogenase; WBC: White blood cells; NEUT: Neutrophil granulocyte; PLT: Blood platelet; PT: Prothrombin time; INR: International normalized ratio; FgB: Fibrinogen; APTT: Activated partial thromboplastin time; TT: Thrombin time.

Citation: Yuan XX, Zhu HJ, Pan H, Chen S, Liu ZY, Li Y, Wang LJ, Lu L, Yang HB, Gong FY. Clinical characteristics of non-alcoholic fatty liver disease in Chinese adult hypopituitary patients. World J Gastroenterol 2019; 25(14): 1741-1752
URL: https://www.wjgnet.com/1007-9327/full/v25/i14/1741.htm
DOI: https://dx.doi.org/10.3748/wjg.v25.i14.1741