Ursodeoxycholic acid ameliorates hepatic lipid metabolism in LO2 cells by regulating the AKT/mTOR/SREBP-1 signaling pathway

Figure 3 Alteration of CRTC2/SREBP-1 signaling pathway under the condition of ursodeoxycholic acid in oleic acid-induced LO2 cells. A: CRTC2 activity and nSREBP-1 expression detected by Western blot assay. B: Relative quantitative analysis of phosphorylated CRTC2 and mature SREBP-1 in LO2 cells. Data are shown as the mean ± SE. ^bP < 0.01, ns vs ctrl group; ^cP < 0.01 vs model group. Ctrl: Control; UDCA: Ursodeoxycholic acid; ns: no significant statistical difference.