Diffusion-weighted magnetic resonance imaging and micro-RNA in the diagnosis of hepatic fibrosis in chronic hepatitis C virus

Table 1 Comparison of demographic and laboratory data in F0, early fibrosis, and late fibrosis groups

Parameter	Control, n = 82	Early fibrosis, n = 112	Late fibrosis, n = 96	P value
Age	38.3 ± 10.2	34.1 ± 8.9	41.4 ± 7.823	0.001
Gender (M:F)	47:35	69:43	60:36	0.8
ALT	36.29 ± 17.24	52.00 ± 36.071	57.17 ± 36.8823	0.001
AST	35.00 ± 15.71	49.00 ± 25.121	58.00 ± 35.1223	0.001
Albumin	4.10 ± 0.45	4.20 ± 0.44	3.80 ± 0.6923	0.001
Bilirubin	0.88 ± 0.48	0.81 ± 0.26	1.02 ± 0.462	0.001
PCR	95746 ± 10111	391000 ± 2138761	254500 ± 12931423	0.001
AFP	7.50 ± 1.57	5.01 ± 2.951	10.47 ± 6.7823	0.001

¹Significance between control and early;

²Significance between control and late;

³Significance between late and early. Data expressed as mean and standard deviation, F one way analysis of variance test was used for comparison between the three groups. Student’s t-test was used to compare between each two groups. ALT: Alanine transaminase; AST: Aspartate transaminase; PCR: Polymerase chain reaction; AFP: Alpha-fetoprotein.