Nomograms for predicting pathological response to neoadjuvant treatments in patients with rectal cancer

Table 8 Predictive factors for complete pathological response in univariate logistic regression analysis for the mFOLFOX6-RT regimen

Variable		Non-pCR (n = 81) n P50 (P25-P75)	pCR (n = 45) n P50 (P25-P75)	pCR rate	P-value
Gender	Male	63	35	35.71%	1
	Female	18	10	35.71%
Age (yr)	≤ 60	62	34	35.42%	0.901
	> 60	19	11	36.67%
BMI (kg/cm2)	< 25	49	34	40.96%	0.202
	≥ 25	23	9	28.13%
Hemoglobin (g/L)	≤ 125	23	13	36.11%	0.905
	> 125	41	22	34.92%
NLR	> 3	9	6	40.00%	0.683
	≤ 3	55	29	34.52%
PLT (×109/L)		246.5 (214.25-289.75)	239 (197-269)		0.22
ApoA1 (g/L)		1.26 (1.15-1.44)	1.3 (1.15-1.55)		0.453
ApoB (g/L)		1 (0.81-1.24)	0.97 (0.81-1.17)		0.725
The interval		51.5 (43-58.75)	54 (50-62)		0.116
CEA (ng/mL)	> 5	40	16	28.57%	0.107
	≤ 5	24	19	44.19%
Differentiation	Moderate-poor	63	30	32.26%	0.311
	Well	13	10	43.48%
DTAV (cm)	< 5	33	25	43.10%	0.11
	≥ 5	48	20	29.41%
TL (cm)	> 3	64	27	29.67%	0.008
	≤ 3	13	17	56.67%
TCE	< 50%	8	4	33.33%	0.944
	≥ 50%	65	34	34.34%
cT	2	0	2	100.00%	0.061
	3	58	35	37.63%
	4	18	5	21.74%
cN	+	62	36	36.73%	0.946
	-	16	9	36.00%
MRF	-	49	39	44.32%	0.002
	+	32	6	15.79%

Platelet, apolipoprotein A-1, apolipoprotein B, and the interval were calculated as metrological data, and others are counting data. pCR: Complete pathological response; NLR: Neutrophil-lymphocyte ratio; DTAV: Distance of tumor from the anal verge; TL: Tumor length; TCE: Tumor circumferential extent; PLT: Platelet; ApoA1: Apolipoprotein A-1; ApoB: Apolipoprotein B; MRF: Mesorectal fascia; CEA: Carcinoembryonic antigen.