Nomograms for predicting pathological response to neoadjuvant treatments in patients with rectal cancer

Table 10 Predictive factors for complete pathological response in univariate logistic regression analysis for the mFOLFOX6 regimen

Variable		Non-pCR (n = 148) n P50 (P25-P75)	pCR (n = 14) n P50 (P25-P75)	pCR rate	P-value
Gender	Male	99	8	7.48%	0.418
	Female	47	6	11.32%
Age (yr)	≤ 60	92	10	9.80%	0.532
	> 60	54	4	6.90%
BMI (kg/cm2)	< 25	107	11	9.32%	0.477
	≥ 25	34	2	5.56%
Hemoglobin (g/L)	≤ 125	53	2	3.64%	0.093
	> 125	75	10	11.76%
NLR	> 3	16	1	5.88%	0.673
	≤ 3	112	11	8.94%
PLT (×109/L)		127.5 (117.5-139)	137.5 (127-142.25)		0.82
ApoA1 (g/L)		1.28 (1.11-1.42)	1.3 (1.15-1.46)		0.542
ApoB (g/L)		0.96 (0.77-1.13)	1.13 (0.86-1.3)		0.051
The interval		21.5 (18-25)	25 (19.25-26.75)		0.09
CEA (ng/mL)	> 5	72	7	8.86%	0.889
	≤ 5	56	5	8.20%
Differentiation	Moderate-poor	129	6	4.44%	0
	Well	14	6	30.00%
DTAV (cm)	< 5	55	7	11.29%	0.345
	≥ 5	93	7	7.00%
TL (cm)	> 3	99	6	5.71%	0.02
	≤ 3	37	8	17.78%
TCE	< 50%	19	3	13.64%	0.413
	≥ 50%	112	10	8.20%
cT	2	9	1	10.00%	0.974
	3	101	11	9.82%
	4	22	2	8.33%
cN	+	100	10	9.09%	0.866
	-	36	4	10.00%
MRF	-	108	11	9.24%	0.707
	+	38	3	7.32%

Platelet, apolipoprotein A-1, apolipoprotein B, and the interval were calculated as metrological data, and others are counting data. pCR: Complete pathological response; NLR: Neutrophil-lymphocyte ratio; DTAV: Distance of tumor from the anal verge; TL: Tumor length; TCE: Tumor circumferential extent; PLT: Platelet; ApoA1: Apolipoprotein A-1; ApoB: Apolipoprotein B; MRF: Mesorectal fascia; CEA: Carcinoembryonic antigen.