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©The Author(s) 2018.
World J Gastroenterol. Mar 7, 2018; 24(9): 971-981
Published online Mar 7, 2018. doi: 10.3748/wjg.v24.i9.971
Published online Mar 7, 2018. doi: 10.3748/wjg.v24.i9.971
Table 4 Fluoroquinolone resistance rates and the distribution of resistance-mediating mutations
| Genotype | Number of gastric biopsy specimens n (%) | P value1 | ||
| All patients 165 (100) | Treatment Naïve 105 (63.6) | Previously treated 60 (36.4) | ||
| FluoroquinoloneS (WT) | 132 (80.0) | 89 (84.8) | 43 (71.7) | |
| FluoroquinoloneR | 33 (20.0) | 16 (15.2) | 17 (28.3) | NS |
| Point mutations | ||||
| gyr91 D91Y | 18 (54.5) | 10 (62.5) | 8 (47.1) | NS |
| gyr91 D91N | 6 (18.2) | 2 (12.5) | 4 (23.5) | NS |
| gyr91 D91G | 2 (6.1) | 0 (0.0) | 2 (11.8) | NS |
| gyr91 D91N + gyr91 D91G | 2 (6.1) | 1 (6.3) | 1 (5.9) | NS |
| gyr91 D91N +gyr91 D91Y | 2 (6.1) | 1 (6.3) | 1 (5.9) | NS |
| gyr87 N87K | 1 (3.0) | 1 (6.3) | 0 (0.0) | NS |
| gyr87 N87K + gyr91 D91N + gyr91 D91G | 1 (3.0) | 0 (0.0) | 1 (5.9) | NS |
| gyr87 N87K + gyr91 D91N + gyr91 D91G + gyr91 D91Y | 1 (3.0) | 1 (6.3) | 0 (0.0) | NS |
- Citation: Brennan DE, Dowd C, O’Morain C, McNamara D, Smith SM. Can bacterial virulence factors predict antibiotic resistant Helicobacter pylori infection? World J Gastroenterol 2018; 24(9): 971-981
- URL: https://www.wjgnet.com/1007-9327/full/v24/i9/971.htm
- DOI: https://dx.doi.org/10.3748/wjg.v24.i9.971