Phenotypic and genotypic characterization of inflammatory bowel disease in children under six years of age in China

Table 3 Comparison of clinical features of monogenic and nonmonogenic inflammatory bowel disease groups

	Nonmonogenic IBD	Monogenic IBD	P value
Diagnosis
CD, %	75.0	50.0
IBD-U, %	18.2	40.0
UC, %	6.8	10.0
Abdominal pain, n	25	2	0.142
Diarrhea, n	36	8	1.000
Bloody stools, n	26	8	0.131
Malnutrition, n	19	5	0.489
Growth failure, n	14	4	0.461
Oral ulcers, n	3	1	0.529
Persistent fever, n	3	0	1.000
Perianal diseases, n	9	7	0.001a
Body weight Z-score	-1.54 (-4.69, 2.20)	-2.04 (-3.66, 0.96)	0.303
Height Z-score	-1.38 (-6.43, 2.51)	-1.76 (-4.92, 0.46)	0.597
WBC, as a109	15.04 ± 1.72	12.53 ± 1.72	0.382
HGB, in g/L	103.02 ± 2.57	106.67 ± 5.00	0.496
PLT, as a1012	454.60 ± 28.40	421.89 ± 54.97	0.632
CRP, in mg/L	51.16 ± 8.43	20.22 ± 2.43	0.668
ESR, in mm/h	29.22 ± 4.70	21.00 ± 4.56	0.923
ALB, in g/L	33.80 ± 1.10	36.60 ± 1.77	0.283
Steroid, n	36	6	0.399
Antibiotics, n	29	7	0.484
Mesalazine, n	32	2	0.009a
Immunosuppressants, n	25	8	0.075
Nutrition, n	33	5	0.425
Infliximab, n	14	4	0.461
Surgery, n	6	4	0.050
Death, n	5	1	0.000a

^aP < 0.05. IBD: Inflammatory bowel disease.