Comparison of TPMT and NUDT15 polymorphisms in Chinese patients with inflammatory bowel disease

doi:10.3748/wjg.v24.i8.941

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Feb 28, 2018 (publication date) through Nov 30, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Feb 28, 2018; 24(8): 941-948
Published online Feb 28, 2018. doi: 10.3748/wjg.v24.i8.941

Table 1 Characteristics of patients

	UC	CD	UIBD	Total
No. of patients (n)	39 (17.8)	176 (80.4)	4 (1.8)	219
Age in yr	42.74 ± 13.60	30.51 ± 11.84	45.25 ± 16.62	33.44 ± 13.08
Sex, M/F	27/12	132/44	1/3	161/59
TPMT genotype
A/A	38 (97.4)	174 (98.9)	4 (100)	216 (98.6)
A/G^a	1 (2.6)	2 (1.1)	0	3 (1.4)
NUDT15 genotype
C/C	31 (79.5)	140 (79.5)	4 (100)	175 (79.9)
C/T	8 (20.5)	36 (20.5)	0	44 (20.1)
AZA therapy	3 (7.7)	77 (43.8)	0	80 (36.5)

Data are presented as n (%) or mean ± SD.

^aP < 0.05 vs NUDT15 C/T. CD: Crohn’s disease; UC: Ulcerative colitis; UIBD: Undetermined inflammatory bowel disease, AZA: Azathioprine.

Citation: Wang HH, He Y, Wang HX, Liao CL, Peng Y, Tao LJ, Zhang W, Yang HX. Comparison of TPMT and NUDT15 polymorphisms in Chinese patients with inflammatory bowel disease. World J Gastroenterol 2018; 24(8): 941-948
URL: https://www.wjgnet.com/1007-9327/full/v24/i8/941.htm
DOI: https://dx.doi.org/10.3748/wjg.v24.i8.941