Intravoxel incoherent motion diffusion-weighted magnetic resonance imaging for predicting histological grade of hepatocellular carcinoma: Comparison with conventional diffusion-weighted imaging

Table 1 Intravoxel incoherent motion diffusion-weighted imaging parameters of different pathologic grades of hepatocellular carcinoma

Parameter	Observer	Edmondson-Steiner grade			P value
		1 (n = 14)	2 (n = 24)	3 (n = 24)
ADC (× 10-3 mm2/s)1	R1	1.496 ± 0.312	1.210 ± 0.186	1.003 ± 0.247	< 0.001
	R2	1.503 ± 0.306	1.214 ± 0.186	1.001 ± 0.236	< 0.001
D (× 10-3 mm2/s)1	R1	1.186 ± 0.214	0.910 ± 0.151	0.775 ± 0.188	< 0.001
	R2	1.193 ± 0.226	0.910 ± 0.148	0.771 ± 0.187	< 0.001
D* (× 10-3 mm2/s)2	R1	37.400 (43.900)	29.000 (71.700)	7.980 (63.590)	0.057
	R2	32.200 (44.600)	28.400 (74.363)	7.885 (61.640)	0.054
f (%)2	R1	27.250 (14.925)	20.675 (11.225)	31.300 (12.267)	0.149
	R2	26.550 (20.200)	21.200 (11.725)	31.550 (11.325)	0.214

¹Data are mean ± SD, one-way analysis of variance;

²data are median (interquartile range), Kruskal-Wallis Test. A P-value < 0.05 was considered statistically significant. R1: Radiologist 1; R2: Radiologist 2; ADC: Apparent diffusion coefficient; D: Pure diffusion coefficient; D*: Pseudo-diffusion coefficient; f: Perfusion fraction.