Predictors of post-treatment stenosis in cervical esophageal cancer undergoing high-dose radiotherapy

doi:10.3748/wjg.v24.i7.862

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Feb 21, 2018; 24(7): 862-869
Published online Feb 21, 2018. doi: 10.3748/wjg.v24.i7.862

Table 4 Patients with post-radiotherapy stenosis or tracheoesophageal fistula (n = 19)

Age/Sex	T stage	Involve circumf	Initial stenosis/ management	RT (Gy)	Response	Toxicity (onset, mo)	Outcome (mo)
29/F	T3	100%	Dysphagia only	59.4	CR	Stenosis (20)	NED, alive (152)
70/M	T3	100%	Total obst/none	59.4	PR	Stenosis (5)	DOOC (12)
64/M	T4a	100%	Dysphagia only	63.0	PR	Stenosis (1)	DM (5), DOD (7)
68/F	T3	100%	Dysphagia only	63.0	CR	Stenosis (1)	NED, alive (21)
75/M	T3	100%	Total obst/none	63.0	PR	Stenosis (2)	DOOC (22)
60/F	T4b	100%	Total obst/stent	70.0	CR	Stenosis (4)	NED, alive (23)
68/M	T3	100%	Dysphagia only	70.2	SD	Stenosis (6)	InF (8), DOD (14)
73/M	T4b	75%	Total obst/stent	90.0¹	PR	Stenosis (11)	DM (13), DOD (17)
64/M	T3	100%	Dysphagia only	50.4	PR	Stenosis² (9)	InF (17), DOD (20)
69/M	T4b	100%	Total obst/stent	50.4	SD	Stenosis² (2)	DOOC (5)
64/M	T4a	100%	Dysphagia only	59.4	PR	Stenosis² (7)	DM (3)/InF (9), DOD (11)
68/M	T3	100%	Total obst/none	63.0	PR	Stenosis² (2)	DM (3), DOD (5)
73/M	T3	100%	Total obst/PEG	63.0	PR	Stenosis² (22)	InF (16), DOD (31)
75/M	T3	40%	Dysphagia only	57.6	CR	Stenosis² (14)	InF (7), DOD (31)
74/M	T3	50%	Dysphagia only	81.0¹	CR	Stenosis² (9)	InF (9), DOD (16)
57/M	T3	100%	Dysphagia only	63.0	PR	TEF (3)	OutF (8), DOD (9)
57/M	T3	100%	Total obst/stent	60.0	CR	Stenosis (1)/TEF² (6)	InF (8), DOD (14)
72/M	T3	100%	Total obst/stent	63.0	PR	TEF² (2)	DOOC (5)
51/M	T3	40%	Dysphagia only	63.0	PR	TEF² (2)	RF (4), DOD (6)

¹Boost RT (18-27 Gy) was delivered to residual tumor 1-2 mo after 63 Gy.

²Malignant complications. Involve circumf: Percent of esophageal circumference involved by tumor; RT: Radiotherapy; obst: Obstruction; PEG: Percutaneous endoscopic gastrostomy; CR: Complete response; PR: Partial response; SD: Stable disease; InF: Infield failure; OutF: Outfield failure; RF: Regional failure; DM: Distant metastasis; DOD: Died of disease; DOOC: Died of other cause; NED: No evidence of disease; TEF: Tracheoesophageal fistula.

Citation: Kim JW, Kim TH, Kim JH, Lee IJ. Predictors of post-treatment stenosis in cervical esophageal cancer undergoing high-dose radiotherapy. World J Gastroenterol 2018; 24(7): 862-869
URL: https://www.wjgnet.com/1007-9327/full/v24/i7/862.htm
DOI: https://dx.doi.org/10.3748/wjg.v24.i7.862