Translational pancreatic cancer research: A comparative study on patient-derived xenograft models

Table 3 Impact of histology on experimental models n (%)

	Human (n = 11)	Subcutaneous (n = 23)	Intraperitoneal (n = 17)	Pancreas (n = 16)	P1 value
Impact of differentiation
Differentiated	2 (18.2)	7 (30.4)	5 (29.4)	3 (18.8)	0.205
Moderately differentiated	8 (72.7)	7 (30.4)	4 (23.5)	8 (50)
Undifferentiated	1 (9.1)	9 (39.1)	8 (47.1)	5 (31.3)
Impact of fibrosis
Mild	4 (36.3)	12 (52.1)	6 (35.2)	6 (37.5)	0.044
Moderate	3 (27.2)	5 (21.7)	9 (52.9)	3 (18.8)
High	0 (0)	4 (17.3)	2 (11.7)	5 (31.3)
Very high	4 (36.3)	2 (8.6)	0 (0)	2 (12.5)

¹Statistical analyses were performed by the χ² exact test, with P < 0.05 considered statistically significant.