Performance of transient elastography in assessing liver fibrosis in patients with autoimmune hepatitis-primary biliary cholangitis overlap syndrome

Table 2 Diagnostic accuracy of liver stiffness measurement in detecting liver fibrosis in patients with autoimmune hepatitis-primary biliary cholangitis overlap syndrome

Stage	AUROC (95%CI)	Cut-off (kPa)	Sensitivity	Specificity	PPV	NPV	+LR	-LR
F ≥ 2	0.837 (0.729-0.914)	6.55	0.902	0.778	0.965	0.538	4.06	0.13
F ≥ 3	0.910 (0.817-0.965)	10.50	0.844	0.921	0.900	0.875	10.69	0.17
F = 4	0.966 (0.893-0.995)	14.45	1.000	0.889	0.500	1.000	9.00	0.00

AUROC: Areas under the receiver operator characteristic; PPV: Positive predictive value; NPV: Negative predictive value; +LR: Positive likelihood ratio; -LR: Negative likelihood ratio.