Incidence of hepatocellular carcinoma in patients with chronic liver disease due to hepatitis B or C and coinfected with the human immunodeficiency virus: A retrospective cohort study

Table 1 Characteristics of patients with chronic liver disease due to hepatitis B or C virus, with and without human immunodeficiency virus

Characteristics	HIV+ (n = 399)	HIV- (n = 405)	P value
Age, yr	36.7 ± 10	46.3 ± 12.5	< 0.001
Male gender	249 (62.4)	197 (48.6)	< 0.001
Caucasian	285 (71.4)	352 (86.9)	< 0.001
	n = 390	n = 343
Diabetes or glucose intolerance	57 (14.6)	100 (29.2)	< 0.001
	n = 247	n = 184
Illicit drugs	161 (65.2)	41 (22.3)	< 0.001
	n = 283	n = 269
Alcohol	119 (42.0)	96 (35.7)	0.138
	n = 399	n = 404
Hepatitis B	82 (20.6)	49 (12.1)	0.002
	n = 81	n = 35
Treatment	77 (95.1)	13 (37.1)	< 0.001
	n = 395	n = 399
Hepatitis C	333 (84.3)	361 (90.5)	0.010
	n = 292	n = 296
Genotype 1	192 (65.8)	157 (53.0)	0.005
Genotype 2	19 (6.5)	17 (5.7)
Genotype 3	79 (27.1)	119 (40.2)
Other1	2 (0.7)	3 (1.0)
	n = 325	n = 338
Treatment	102 (31.4)	151 (44.7)	< 0.001
	n = 399	n = 405
Hospital admissions	359 (90.0)	249 (61.5)	< 0.001
	n = 399	n = 399
Cirrhosis	66 (16.5)	125 (31.3)	< 0.001

Data presented as average ± SD or n (%).

¹Other related genotypes (genotype 4, genotype associations between 1 and 4, 1 and 2, 3 and 4). HIV: Human immunodeficiency virus.