Counteraction of perforated cecum lesions in rats: Effects of pentadecapeptide BPC 157, L-NAME and L-arginine

Figure 3 Bleeding time after perforation. At 1 min post-injury, administration of medication (/kg, 10 mL/2 min bath/rat) at the perforated (5 mm diameter) cecum lesion and cecum includes BPC 157 (10 μg) (B), NOS blocker L-NAME (5 mg) (N), NOS substrate L-arginine (100 mg) (A) alone or combined, and a saline bath of equal volume (controls) (S). Rats were then left after abdominal closure undisturbed until sacrifice, at day 1 or day 7. ^aP < 0.05 at least vs control (S).