Novel screening test for celiac disease using peptide functionalised gold nanoparticles

Figure 4 Detection of anti-gliadin in spiked human serum using peptide-coated AuNPs. A: Reduction in color from red to translucent as well as precipitate formation was observed in AuNP coated with peptide in the presence of AGA and serum at different concentrations (S1-S10). No reduction in color from red to translucent or precipitate formation was observed in AuNP coated with peptide in the presence of control IgG and serum (C1-C10); B: Colorimetric response curve plotted in AuNP coated with peptide in 1:20 diluted serum following the addition of AGA at different dilutions. AGA: Anti-gliadin.