Bypassing major venous occlusion and duodenal lesions in rats, and therapy with the stable gastric pentadecapeptide BPC 157, L-NAME and L-arginine

Figure 8 Nitric oxide levels and malondialdehyde levels in the duodenal tissue of superior anterior pancreaticoduodenal vein-ligated rats at 5 min, 30 min and 24 h ligation. BPC 157 [10 μg/kg, 1 mL bath/rat (Bb), 1 mL instilled into the stomach (Big)] or an equal volume of a saline bath (CONb) or instillation in the stomach (CONig) (controls) was applied to superior anterior pancreaticoduodenal vein-ligated rats. ^aP < 0.05 vs saline; ^bP < 0.05 vs healthy duodenum. H: Healthy duodenum; Bb: BPC 157 10 μg/kg, 1 mL bath/rat; Big: BPC 157 10 μg/kg, 1 mL instilled into the stomach; CONb: 1 mL saline bath; CONig: 1 mL saline instillation in the stomach; NO: Nitric oxide; MDA: Malondialdehyde.