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©The Author(s) 2018.
World J Gastroenterol. Dec 21, 2018; 24(47): 5351-5365
Published online Dec 21, 2018. doi: 10.3748/wjg.v24.i47.5351
Published online Dec 21, 2018. doi: 10.3748/wjg.v24.i47.5351
Table 1 Relative quantification of mRNA expression of the inflammatory genes in adenoma and colorectal cancer samples compared with adjacent normal tissue samples and colorectal cancer samples relative to the adenoma group
TLR2 | TLR4 | NFKB1 | IL1B | IL6 | IL8 | TNF | |
CRA | |||||||
RQ median | 0.87 | 2.27 | 1.02 | 2.27 | 1.12 | 3.33 | 0.75 |
RQ Range | 0.36-10.80 | 0.32-11.25 | 0.45-3.38 | 0.14-76.76 | 0.09-80.41 | 0.10-874.50 | 0.14-2.60 |
P value | 0.2940 | 0.0003a | 0.5360 | 0.0047a | 0.2473 | 0.0006a | 0.0527 |
CRC | |||||||
RQ median | 2.36 | 0.74 | 0.90 | 4.13 | 6.67 | 6.36 | 0.72 |
RQ Range | 0.31-35.80 | 0.20-23.42 | 0.31-8.49 | 0.13-245.70 | 0.09-192.80 | 0.16-194.20 | 0.06-31.76 |
P value | < 0.0001a | 0.4476 | 0.9855 | < 0.0001a | < 0.0001a | < 0.0001a | 0.2391 |
CRC/CRA | |||||||
RQ median | 1.68 | 0.54 | 0.78 | 4.79 | 9.40 | 12.14 | 0.70 |
RQ Range | 0.22-25.49 | 0.15-17.22 | 0.27-7.35 | 0.15-284.80 | 0.13-271.80 | 0.31-370.60 | 0.06-30.77 |
P value | < 0.0001a | 0.0608 | 0.1237 | < 0.0001a | < 0.0001a | < 0.0001a | 0.1560 |
- Citation: Proença MA, Biselli JM, Succi M, Severino FE, Berardinelli GN, Caetano A, Reis RM, Hughes DJ, Silva AE. Relationship between Fusobacterium nucleatum, inflammatory mediators and microRNAs in colorectal carcinogenesis. World J Gastroenterol 2018; 24(47): 5351-5365
- URL: https://www.wjgnet.com/1007-9327/full/v24/i47/5351.htm
- DOI: https://dx.doi.org/10.3748/wjg.v24.i47.5351