Effect of photodynamic therapy with (17R,18R)-2-(1-hexyloxyethyl)-2-devinyl chlorine E6 trisodium salt on pancreatic cancer cells in vitro and in vivo

Figure 4 (17R,18R)-2-(1-hexyloxyethyl)-2-devinyl chlorine E6 trisodium salt-induced photodynamic therapy promotes pancreatic cancer cell apoptosis in vitro. A: Analysis of apoptosis rate by flow cytometry at 4 h post photodynamic therapy. B: Bcl-2, Bax, and, cleaved Caspase-3 protein levels determined by Western blot. β-actin was used as an internal reference. Data are expressed as the mean ± SD (n = 3). ^aP < 0.05, ^bP < 0.01, and ^cP < 0.001 vs the Con group. YLG-1: (17R,18R)-2-(1-hexyloxyethyl)-2-devinyl chlorine E6 trisodium salt; PDT: Photodynamic therapy.