Glucocorticoid receptor regulates expression of microRNA-22 and downstream signaling pathway in apoptosis of pancreatic acinar cells

Figure 4 Expression of Nr3c1 mRNA, glucocorticoid receptor protein, and microRNA-22 level after transfection. A: The levels of Nr3c1 mRNA, GR protein, and miR-22 after transfection with Nr3c1 plasmid; B: The levels of Nr3c1 mRNA, glucocorticoid receptor protein, and miR-22 after transfection with si-Nr3c1. Data were obtained from three independent experiments in triplicate and are shown as the mean ± SD. ^bP < 0.01, ^cP < 0.001 vs plasmid NC or siRNA NC groups. GR: Glucocorticoid receptor; miR-22: MicroRNA-22.