Glucocorticoid receptor regulates expression of microRNA-22 and downstream signaling pathway in apoptosis of pancreatic acinar cells

Figure 1 The apoptosis rate and levels of amylase, apoptosis-associated proteins, and microRNA-22 in caerulein-induced AR42J cells. A: The apoptosis rate of AR42J cells after incubation with caerulein for 24 h; B: Amylase levels in the medium; C: Western blot analysis of the levels of apoptosis-associated proteins in AR42J cells; D: MicroRNA-22 levels in AR42J cells. Data were obtained from three independent experiments performed in triplicate and are shown as the mean ± SD. ^aP < 0.05, ^bP < 0.01, ^cP < 0.001 vs control group. Cae: Caerulein; miR-22: MicroRNA-22.