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©The Author(s) 2018.
World J Gastroenterol. Dec 7, 2018; 24(45): 5154-5166
Published online Dec 7, 2018. doi: 10.3748/wjg.v24.i45.5154
Published online Dec 7, 2018. doi: 10.3748/wjg.v24.i45.5154
Table 1 Summary of clinical, endoscopic, and histopathological characteristics of the 199 pT1N0 esophageal squamous cell carcinoma patients n (%)
| Characteristic | Patients | |
| Clinical variable | ||
| Sex | Male | 142 (71) |
| Female | 57 (29) | |
| Age (yr) | < 60 | 121 (61) |
| ≥ 60 | 78 (39) | |
| Symptoms | No | 13 (7) |
| Yes | 186 (93) | |
| Endoscopic variable | ||
| Tumor location | Upper thoracic | 31 (16) |
| Middle thoracic | 143 (72) | |
| Lower thoracic | 25 (13) | |
| Tumor size (measured endoscopically) | < 2 cm | 59 (30) |
| ≥ 2 cm | 140 (70) | |
| Macroscopic tumor type | Erosive | 73 (37) |
| Papillary | 26 (13) | |
| Plaque-like | 79 (40) | |
| Ulcerative | 9 (5) | |
| Intraluminal mass | 12 (6) | |
| Standard histopathological variable | ||
| Tumor invasion depth level | m2 | 21 (11) |
| m3 | 26 (13) | |
| sm1 | 18 (9) | |
| sm2 | 45 (23) | |
| sm3 | 89 (45) | |
| Degree of differentiation | Well | 39 (20) |
| Moderate | 76 (38) | |
| Poor | 56 (28) | |
| Basaloid | 19 (10) | |
| Spindle cell/sarcomatoid | 9 (5) | |
| Angiolymphatic invasion | No | 172 (86) |
| Yes | 27 (14) | |
| Multicentric invasive lesions | No | 183 (92) |
| Yes | 16 (8) | |
| Number of lymph nodes dissected | < 14 | 90 (45) |
| ≥ 14 | 109 (55) | |
| Measured histopathological variables | ||
| Tumor thickness | < 3000 μm | 85 (43) |
| ≥ 3000 μm | 114 (57) | |
| Submucosal invasion thickness | 0 | 47 (24) |
| 0-2000 μm | 85 (43) | |
| ≥ 2000 μm | 67 (34) | |
| Diameter of the largest single tongue of invasion | < 2 cm | 134 (67) |
| ≥ 2 cm | 65 (33) | |
| Immunohistochemical staining1 | ||
| P53 | Complete loss | 50 (39) |
| Weak, patchy | 41 (32) | |
| Diffuse, strong | 37 (29) | |
| Cyclin D1 | - | 38 (30) |
| 1+ | 39 (31) | |
| 2+ | 49 (39) | |
| EGFR | - | 52 (41) |
| 1+ | 44 (34) | |
| 2+ | 32 (25) | |
| VEGF | - | 54 (44) |
| 1+ | 34 (28) | |
| 2+ | 35 (28) |
- Citation: Xue LY, Qin XM, Liu Y, Liang J, Lin H, Xue XM, Zou SM, Zhang MY, Zhang BH, Hui ZG, Zhao ZT, Ren LQ, Zhang YM, Liu XY, Yuan YL, Ying JM, Gao SG, Song YM, Wang GQ, Dawsey SM, Lu N. Clinicopathological parameters predicting recurrence of pT1N0 esophageal squamous cell carcinoma. World J Gastroenterol 2018; 24(45): 5154-5166
- URL: https://www.wjgnet.com/1007-9327/full/v24/i45/5154.htm
- DOI: https://dx.doi.org/10.3748/wjg.v24.i45.5154