Involvement of methylation-associated silencing of formin 2 in colorectal carcinogenesis

Figure 3 Promoter hypermethylation and formin 2 expression are causally related. A: Results of MethylTarget^™ assays on four colorectal cancer cell lines and normal colon cells from a healthy individual; B: The inhibition of DNA methylation with 5-Aza significantly increased the endogenous FMN2 expression (unpaired t-test).