Different distributions of interstitial cells of Cajal and platelet-derived growth factor receptor-α positive cells in colonic smooth muscle cell/interstitial cell of Cajal/platelet-derived growth factor receptor-α positive cell syncytium in mice

Figure 7 Fast inhibitory junction potential and slow inhibitory junction potential elicited by electrical field stimulation in smooth muscles of the proximal and distal colon. A and B: Atropine and L-NAME treatment blocked excitatory junction potentials (EJPs) and decreased slow inhibitory junction potentials (sIJPs) but had no effect on fast IJPs (fIJPs) in colonic muscles from both ends. D and E: Atropine and MRS2500 treatment blocked EJPs and decreased fIJPs but had no effect on sIJPs in colonic muscles from both ends. C and F: Summary of data showing the average amplitude of fIJPs and sIJPs (in the presence of atropine and L-NAME, n = 8; in the presence of atropine and MRS2500, n = 7; ^aP < 0.05). fIJP: Fast inhibitory junction potential; sIJP: Slow inhibitory junction potential.