Different distributions of interstitial cells of Cajal and platelet-derived growth factor receptor-α positive cells in colonic smooth muscle cell/interstitial cell of Cajal/platelet-derived growth factor receptor-α positive cell syncytium in mice

Figure 5 Effects of anoctamin-1 and small conductance calcium-activated potassium channel 3 channel antagonist treatment on membrane potentials in the murine colon. A: Summary of the resting membrane potentials of colonic smooth muscle cells from the proximal and distal colon of mice (n = 12; ^aP < 0.05). B: Responses of membrane potentials to anoctamin-1 (ANO1) antagonist treatment (NPPB, 3 μmol/L, arrow). C: Responses of membrane potentials to SK3 antagonist treatment (apamin, 300 nmol/L, arrow). D and E: Summary of data showing the average effects of NPPB and apamin on membrane potentials in colonic smooth muscle cells from both ends of the colon (NPPB n = 6; apamin n = 5; ^aP < 0.05). RMP: Resting membrane potentials.