Establishment, functional and genetic characterization of three novel patient-derived rectal cancer cell lines

Figure 5 ¹⁸F-fluorodeoxyglucose and ¹⁸F-fluorothymidine uptake. Subconfluent-growing rectal cancer cells were either radiated (50 Gy), treated with FOLFOX (IC₂₅) or challenged with combinations thereof. Rectal cancer cells were incubated with ¹⁸F-fluorodeoxyglucose or ¹⁸F-fluorothymidine, and uptake was quantified as described in the “materials and methods” section. Counts per minute were normalized to total protein content of the samples. One hundred percent ¹⁸F uptake corresponds to solvent-treated cancer cells (n = 10); ^aP < 0.05 vs control cultures (Kruskal-Wallis test with post hoc Dunn’s test). ¹⁸F-FDG: ¹⁸F-fluorodeoxyglucose; ¹⁸F-FLT: ¹⁸F-fluorothymidine.