Establishment, functional and genetic characterization of three novel patient-derived rectal cancer cell lines

Figure 4 Analysis of chemo- and radiosensitivity. A: Sensitivity of individual rectal cancer cell lines to FOLFOX and FOLFIRI chemotherapy; B: Sensitivity of cell lines to combination of irradion with 50 Gy and chemotherapy with FOLFIRI or FOLFOX; C: Radiosensitivity of rectal cancer cells. Cells were irradiated to different doses using a ¹³⁷Cs-source. Cell viability of all experiments was measured using crystal violet assay. Values represent the mean absorbance at 570 nm ± SEM of n = 3 analyses; t-test ^aP < 0.05 vs control, ^bP < 0.01 vs control, ^cP < 0.0001 vs control.