Establishment, functional and genetic characterization of three novel patient-derived rectal cancer cell lines

doi:10.3748/wjg.v24.i43.4880

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Nov 21, 2018; 24(43): 4880-4892
Published online Nov 21, 2018. doi: 10.3748/wjg.v24.i43.4880

Table 3 Half maximal inhibitory concentration values of antitumor drugs

Cell line	5-FU (μg/mL)	Irinotecan (μmol/L)	Oxaliplatin (μg/mL)
HROC126	0.42	0.72	0.3
HROC239 T0 M1	21	4.4	2.4
HROC284Met	7	4.3	0.68
Plasma levels (pharmacokinetic)	50	10	2

Values are given as mean, resulting from at least three independent experiments each performed in triplicates. 5-FU: 5-Fluorouracil.

Citation: Gock M, Mullins CS, Bergner C, Prall F, Ramer R, Göder A, Krämer OH, Lange F, Krause BJ, Klar E, Linnebacher M. Establishment, functional and genetic characterization of three novel patient-derived rectal cancer cell lines. World J Gastroenterol 2018; 24(43): 4880-4892
URL: https://www.wjgnet.com/1007-9327/full/v24/i43/4880.htm
DOI: https://dx.doi.org/10.3748/wjg.v24.i43.4880