Copyright
©The Author(s) 2018.
World J Gastroenterol. Nov 14, 2018; 24(42): 4738-4749
Published online Nov 14, 2018. doi: 10.3748/wjg.v24.i42.4738
Published online Nov 14, 2018. doi: 10.3748/wjg.v24.i42.4738
Figure 1 CXCL and CXCR regulatory mechanisms.
Figure 1 illustrates CXCL binding to the CXCR located at the cellular membrane, internalizing and transducing the signal into the nucleus. CXCR internalization is usually followed by degradation or recycling to the plasma membrane.
- Citation: Heras SCDL, Martínez-Balibrea E. CXC family of chemokines as prognostic or predictive biomarkers and possible drug targets in colorectal cancer. World J Gastroenterol 2018; 24(42): 4738-4749
- URL: https://www.wjgnet.com/1007-9327/full/v24/i42/4738.htm
- DOI: https://dx.doi.org/10.3748/wjg.v24.i42.4738