Prediction of colorectal tumor grade and invasion depth through narrow-band imaging scoring

Table 3 Relationship of narrow-band imaging findings to colorectal tumor tissue architecture

	Variable	Classification1	Tissue architecture
			Lining epithelium degeneration/ prolapse	Glandular duct arrangement	Superficial differentiation	Superficial desmoplastic reaction	Muscularis mucosae	Granuloma formation
Surface pattern	Visible/Invisible	Tubular	a	a	a	a	a	a
		Papillary	b	c	c	a	a	a
	Clarity	Tubular	a	a	c	c	a	a
		Papillary	a	a	c	n.a.	a	a
	Regular/Irregular	Tubular	a	a	b	c	a	b
		Papillary	a	a	c	n.a.	a	a
Vascular pattern	Disturbed arrangement	Tubular	a	a	a	a	a	a
		Papillary	a	a	b	c	a	a
	Disrupted vessels	Tubular	a	a	c	a	a	a
		Papillary	a	a	c	a	a	a
	Varying caliber	Tubular	a	a	c	a	a	b
		Papillary	c	c	c	a	b	b
	Size irregularity	Tubular	a	a	a	a	a	a
		Papillary	a	a	b	c	a	a
	Thick vessels	Tubular	a	a	b	a	a	c
		Papillary	a	c	c	c	c	b
	Avascular area	Tubular	a	a	a	a	a	a
		Papillary	c	c	c	b	c	c
	Vessel meandering	Tubular	c	c	c	c	c	c
		Papillary	a	b	c	c	a	a

¹Colorectal lesions were classified into tubular and papillary types based on narrow-band imaging observations of the histopathologic appearances and proliferation patterns. ^aP < 0.05; 0.05 < ^bP < 0.1; ^cP > 0.1. n.a.: Not available.