Prediction of colorectal tumor grade and invasion depth through narrow-band imaging scoring

Table 1 Relationship of narrow-band imaging findings with tumor grade and invasion depth

	Dependent variable	Independent variable1	Univariate analysis		Multivariate analysis
			Odds ratio (95%CI)	P value	Odds ratio (95%CI)	P value
Tumor grade	Probability of cancer	Irregular (tubular type)	0.034 [0.013, 0.088]	< 0.0001	46.81 [14.55, 184.48]	< 0.0001
	AUC = 0.89	Irregular (papillary type)	0.034 [0.013, 0.088]	< 0.0001	47.21 [7.51, 512.05]	< 0.0001
		Avascular area	0.048 [0.006, 0.376]	< 0.0001	16.3 [1.69, 396.35]	0.06
Invasion depth	Probability of SM deep invasive cancer2	Disrupted vessels	0.169 [0.058, 0.488]	0.0004	3.63 [0.98, 17.69]	0.0714
	AUC = 0.70	Thick vessels	0.509 [0.127, 2.037]	0.3325	22.86 [2.55, 537.18]	0.0133

¹Colorectal lesions were classified into tubular and papillary types based on narrow-band imaging observations of the histopathologic appearances and proliferation patterns;

²Submucosa (SM) deep invasive cancer: SM invasion depth ≥ 1000 μm. SM: Submucosa; AUC: Area under the curve.