Mucosal adhesion and anti-inflammatory effects of Lactobacillus rhamnosus GG in the human colonic mucosa: A proof-of-concept study

Figure 6 Lactobacillus rhamnosus GG adhesion and mucosal effect in the colon of ulcerative colitis patients. A: Mucosal Lactobacillus rhamnosus GG (LGG) quantification in colon biopsies of ulcerative colitis (UC) patients who consumed a regular (12 × 10⁹ UFC/die) or a double (24 × 10⁹ UFC/die) dose of LGG supplement for 7 d (n = 10 per group); B: Tumor necrosis factor alpha mRNA quantification in colon biopsies from UC patients who consumed a regular or a double dose of LGG supplement for 7 d. Mean ± standard error is represented; C: Interleukin-17 mRNA quantification in colon biopsies from UC patients who consumed a regular or a double dose of LGG supplement for 7 d. ^aP < 0.05. TNFα: Tumor necrosis factor alpha; IL: Interleukin; LGG: Lactobacillus rhamnosus GG; UC: Ulcerative colitis.