Mucosal adhesion and anti-inflammatory effects of Lactobacillus rhamnosus GG in the human colonic mucosa: A proof-of-concept study

Figure 1 Lactobacillus rhamnosus GG adhesion in the normal colon and ulcerative colitis patients’ colon was evaluated by the ex vivo organ culture experimental model. A: Mucosal Lactobacillus rhamnosus GG (LGG) quantification from total bioptic samples showed consistent adhesion in mucosal biopsies, with a trend toward higher LGG concentrations in distal specimens compared with proximal specimens (n = 20 per group); B: Mucosal LGG quantification from bioptic samples from ulcerative colitis patients confirmed consistent bacterial adhesion after incubation (n = 15 per group). The bars represent the mean values. LGG: Lactobacillus rhamnosus GG; UC: Ulcerative colitis.