Outcomes of furazolidone- and amoxicillin-based quadruple therapy for Helicobacter pylori infection and predictors of failed eradication

Table 2 Helicobacter pylori eradication rates with furazolidone- and amoxicillin-based quadruple therapy: Overall and by subgroup % (95%CI)

Variable	n/N	Eradication rate
Overall	937/992	94.5 (94.1-95.9)
Primary	800/842	95.0 (93.5-96.5)
Rescue	137/150	91.3 (86.8-95.8)
Adverse events1
Without	683/715	95.5 (94.0-97.0)2
With	130/144	90.3 (85.5-95.1)

¹Patients who completed the study protocol were divided into two groups: without or with adverse events during therapy. Eradication rates of two groups were calculated and the difference between the two groups was analyzed.

²Eradication rates were higher among patients without (mean difference = 5.2%, 95%CI: 0.7%-11.7%, P = 0.01) compared to those with adverse events during therapy. n: Number of successful eradication; N: Number of total patients.