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©The Author(s) 2018.
World J Gastroenterol. Oct 28, 2018; 24(40): 4586-4595
Published online Oct 28, 2018. doi: 10.3748/wjg.v24.i40.4586
Published online Oct 28, 2018. doi: 10.3748/wjg.v24.i40.4586
All patients | Surgery-only | All radiotherapy | Postoperative | Preoperative | Long | Short | |
Patient number | 28220 | 21769 | 6451 | 4826 | 1625 | 1311 | 314 |
Male (%) | 16297 (58%) | 12323 (57%) | 3974 (62%) | 2940 (61%) | 1034 (64%) | 831 (63%) | 203 (65%) |
Median follow-up (IQR), yr | 5.19 (5.02) | 5.47 (5.18) | 4.25 (3.98) | 4.29 (4.10) | 4.16 (3.61) | 4.18 (3.76) | 4.10 (3.01) |
Median rectal cancer diagnosis age (IQR) | 65 (18) | 66 (18) | 62 (17) | 62 (18) | 61 (19) | 60 (18) | 64 (18) |
Median rectal cancer diagnosis year (IQR) | 2005 (7) | 2004 (6) | 2006 (6) | 2005 (6) | 2007 (5) | 2007 (5) | 2007 (4) |
Surgery | |||||||
LAR | 20416 | 16253 | 4163 | 2953 | 1210 | 950 | 260 |
APR | 6285 | 4453 | 1832 | 1471 | 361 | 311 | 50 |
Other surgery | 1519 | 1063 | 456 | 402 | 54 | 50 | 4 |
Chemotherapy | |||||||
All chemotherapy (%) | 18236 (65%) | 12310 (57%) | 5926 (92%) | 4445 (92%) | 1481 (91%) | 1276 (97%) | 205 (65%) |
Fluorouracil | 12063 | 7399 | 4664 | 3428 | 1236 | 1105 | 131 |
Tegafur | 11324 | 8139 | 3185 | 2547 | 638 | 517 | 121 |
Oxaliplatin | 4033 | 2460 | 1573 | 1273 | 300 | 262 | 38 |
Irinotecan | 3273 | 2020 | 1253 | 1069 | 184 | 151 | 33 |
Capecitabine | 2620 | 1632 | 988 | 773 | 215 | 185 | 30 |
Comorbidities | |||||||
DM | 10802 | 8560 | 2242 | 1696 | 546 | 427 | 119 |
Hypertension | 18096 | 14438 | 3658 | 2742 | 916 | 720 | 196 |
Liver cirrhosis | 1521 | 1227 | 294 | 225 | 69 | 46 | 23 |
Autoimmune disease | 1763 | 1372 | 391 | 298 | 93 | 76 | 17 |
End stage renal disease | 5456 | 4402 | 1054 | 825 | 229 | 168 | 61 |
COPD | 10762 | 8709 | 2053 | 1585 | 468 | 368 | 100 |
Dyslipidemia | 11695 | 9246 | 2449 | 1779 | 670 | 534 | 136 |
- Citation: Wang TH, Liu CJ, Chao TF, Chen TJ, Hu YW. Second primary malignancy risk after radiotherapy in rectal cancer survivors. World J Gastroenterol 2018; 24(40): 4586-4595
- URL: https://www.wjgnet.com/1007-9327/full/v24/i40/4586.htm
- DOI: https://dx.doi.org/10.3748/wjg.v24.i40.4586