Helicobacter pylori promotes invasion and metastasis of gastric cancer by enhancing heparanase expression

doi:10.3748/wjg.v24.i40.4565

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Oct 28, 2018 (publication date) through Nov 26, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Oct 28, 2018; 24(40): 4565-4577
Published online Oct 28, 2018. doi: 10.3748/wjg.v24.i40.4565

Table 8 Multivariate COX regression analysis

Variable	Overall survival
Variable	HR	95%CI	P value
Lymph metastasis (yes vs no)	4.443	2.185-9.036	0.000
Tissue differentiation (high and medium vs low)	3.452	1.299-9.176	0.013
Invasive depth (T3/4 vs T1/2)	2.542	1.198-5.392	0.015
HPA expression (positive vs negative)	2.463	1.195-5.076	0.015

HPA: Heparanase; HR: Hazard ratio; CI: Confidence interval.

Citation: Liu LP, Sheng XP, Shuai TK, Zhao YX, Li B, Li YM. Helicobacter pylori promotes invasion and metastasis of gastric cancer by enhancing heparanase expression. World J Gastroenterol 2018; 24(40): 4565-4577
URL: https://www.wjgnet.com/1007-9327/full/v24/i40/4565.htm
DOI: https://dx.doi.org/10.3748/wjg.v24.i40.4565