Influence of NUDT15 variants on hematological pictures of patients with inflammatory bowel disease treated with thiopurines

Figure 2 Change of white blood cell counts with or without prednisolone. A: Absolute number of WBC counts in two groups (Groups A + B + C vs D) with PSL. In the cases with prednisolone, WBC count tended to decreased more in the mutant cases (Group A + B + C) and was significantly different at 8 and 10 wk (P = 0.012 and 0.029, respectively); B: Absolute number of WBC counts in two groups (Groups A + B + C vs D) without PSL. In the cases without prednisolone, WBC count was significantly lower at 2, 4, 8 and 14 wk significantly in the mutant (Group A + B + C) than the wild cases (Group D, P = 0.0196, 0.0182, 0.0237 and 0.0241, respectively). PSL: Prednisolone; WBC: White blood cell.