Diet switch and omega-3 hydroxy-fatty acids display differential hepatoprotective effects in an obesity/nonalcoholic fatty liver disease model in mice

doi:10.3748/wjg.v24.i4.461

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Jan 28, 2018 (publication date) through Nov 27, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jan 28, 2018; 24(4): 461-474
Published online Jan 28, 2018. doi: 10.3748/wjg.v24.i4.461

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Figure 6 Liver tissue morphology. Representative photomicrographs (Magnification × 20) Hematoxylin-eosin stain. HFD + DS showed a drastic decrease of number in fat vesicles and ballooning degeneration, but minimal change in inflammatory cells. Both groups HFD + 18-HEPE and HFD + 17-HDHA showed noticeable changes in steatosis and hepatocyte ballooning compared to HFD group. Plus, both groups displayed scarce presence of inflammatory cells.

Citation: Rodriguez-Echevarria R, Macias-Barragan J, Parra-Vargas M, Davila-Rodriguez JR, Amezcua-Galvez E, Armendariz-Borunda J. Diet switch and omega-3 hydroxy-fatty acids display differential hepatoprotective effects in an obesity/nonalcoholic fatty liver disease model in mice. World J Gastroenterol 2018; 24(4): 461-474
URL: https://www.wjgnet.com/1007-9327/full/v24/i4/461.htm
DOI: https://dx.doi.org/10.3748/wjg.v24.i4.461