Diet switch and omega-3 hydroxy-fatty acids display differential hepatoprotective effects in an obesity/nonalcoholic fatty liver disease model in mice

Figure 1 Weight, blood glucose and insulin tolerance test in an obesity/ nonalcoholic fatty liver disease model in C57BL/6 mice. Weight (A), fasting glucose (B), Insulin tolerance test (C) and area under the curve from ITT data (D). All data are mean ± SEM. Groups: CD (n = 6), HFD (n = 6), HFD + DS (n = 6), HFD + 18-HEPE (n = 6), HFD + 17-HDHA (n = 6). ^aP < 0.05 vs CD, ^cP < 0.05 vs HFD by Mann-Whitney U test. HFD: High-fat, fructose-enriched diet.