Novel targeting approaches and signaling pathways of colorectal cancer: An insight

doi:10.3748/wjg.v24.i39.4428

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Oct 21, 2018 (publication date) through Jan 12, 2025

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Oct 21, 2018; 24(39): 4428-4435
Published online Oct 21, 2018. doi: 10.3748/wjg.v24.i39.4428

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Figure 2 Signaling pathways involved in colorectal cancer. TGF-β: Transforming growth factor-β; LRP: Lipoprotein receptor-related protein; Dsh: Phosphoprotein Dishevelled; GSK3: Glycogen synthase kinase-3; CK1: Casein kinase 1; PI3K: Phosphoinositide 3-kinase; PIP2: Phosphatidylinositol biphosphate; PIP3: Phosphatidylinositol 3,4,5-triphosphate; EGF: Epidermal growth factor; EGFR2: Epidermal growth factor receptor 2; BMPR: Bone morphogenetic proteins receptor; BMP: Bone morphogenetic proteins; RAF: Rapidly Accelerated Fibrosarcoma; MEK: Mitogen-activated protein kinase; AKT: Protein kinase B; MAPK: Mitogen-activated protein kinases; SUFU: Suppressor of fused homolog.

Citation: Tiwari A, Saraf S, Verma A, Panda PK, Jain SK. Novel targeting approaches and signaling pathways of colorectal cancer: An insight. World J Gastroenterol 2018; 24(39): 4428-4435
URL: https://www.wjgnet.com/1007-9327/full/v24/i39/4428.htm
DOI: https://dx.doi.org/10.3748/wjg.v24.i39.4428