Sex-specific effects of Eugenia punicifolia extract on gastric ulcer healing in rats

Figure 3 Effects of hydroalcoholic extract from the leaves of Eugenia punicifolia on cell proliferation and migration into the scratch-wound area. A monolayer of L929 fibroblasts was scratched and treated with vehicle or HEEP at different concentrations (3, 10, and 30 μg/mL). A: Images captured at 100 × magnification at 0, 24, and 48 h after incubation; B: Rate of migration, evaluated in terms of the total distance that the cells moved from the edge of the scratch toward the center. The results represent mean ± standard error of the mean in triplicate experiments. Statistical significance was established using analysis of variance (two-way ANOVA) followed by Bonferroni’s test. ^aP < 0.001 vs time-matched vehicle. HEEP: Hydroalcoholic extract from the leaves of Eugenia punicifolia.