Sex-specific effects of Eugenia punicifolia extract on gastric ulcer healing in rats

Figure 1 Effects of 14-d treatment with hydroalcoholic extract from the leaves of Eugenia punicifolia and lansoprazole on gastric ulcer healing in a rat model. Results were expressed as mean ± standard error of the mean in each group (n = 8-10). Values are given as a percentage indicating healing relative to the corresponding vehicle group. Statistical significance was determined using one-way ANOVA followed by Dunnett's test or Student’s t-test. ^aP < 0.05 and ^bP < 0.01 vs vehicle in males; ^cP < 0.0001 vs vehicle in intact females (cycling); ^dP < 0.01 and ^eP < 0.0001 vs vehicle in ovariectomized females; ^fP < 0.01 for HEEP and lansoprazole in intact females vs males; ^gP < 0.01 and ^hP < 0.001 for HEEP and lansoprazole in intact vs ovariectomized females; Ns: not significant; HEEP: Hydroalcoholic extract from the leaves of Eugenia punicifolia.