Sex-specific effects of Eugenia punicifolia extract on gastric ulcer healing in rats

Table 3 Organ weights following the 14-d treatment of ovariectomized rats with acetic acid-induced gastric ulcers with lansoprazole and hydroalcoholic extract from the leaves of Eugenia punicifolia

	Treatment
	Vehicle	Lansoprazole	HEEP
Organ weights, g
Heart	3.35 ± 0.04	3.39 ± 0.05	3.49 ± 0.09
Kidneys	4.52 ± 0.07	4.56 ± 0.07	4.61 ± 0.05
Lung	4.28 ± 0.11	4.30 ± 0.10	4.47 ± 0.17
Liver	10.56 ± 0.16	10.61 ± 0.10	10.60 ± 0.11
Spleen	2.59 ± 0.06	2.68 ± 0.08	2.65 ± 0.05
Biochemical parameters
Glucose, mg/dL	117.30 ± 4.36	126.70 ± 4.48	119.00 ± 5.46
Creatinine, mg/dL	0.42 ± 0.00	0.43 ± 0.01	0.43 ± 0.01
Urea, mg/dL	55.08 ± 2.24	48.97 ± 1.67	55.37 ± 2.92
γ-GT, U/L	< 1.0	< 1.0	< 1.0
AST, U/L	176.80 ± 15.37	192.70 ± 14.77	191.00 ± 21.04
ALT, U/L	62.17 ± 3.68	57.57 ± 2.36	56.43 ± 1.92

Vehicle, lansoprazole, or HEEP was administered for 14 d after ulcer induction. Data were collected at the end of treatment. Results are expressed as the means ± standard error of the mean for each group (n = 7-8). Statistical significance was determined using one-way ANOVA followed by Dunnett's test. No significant differences vs vehicle were noted; ALT: Alanine aminotransferase; AST: Aspartate aminotransferase; γ-GT: Gamma-glutamyl transpeptidase. HEEP: Hydroalcoholic extract from the leaves of Eugenia punicifolia.