Sex-specific effects of Eugenia punicifolia extract on gastric ulcer healing in rats

Table 2 Organ weights following the 14-d treatment of intact female rats with acetic acid-induced gastric ulcers with lansoprazole and hydroalcoholic extract from the leaves of Eugenia punicifolia

	Treatment
	Vehicle	Lansoprazole	HEEP
Organ weights, g
Heart	3.43 ± 0.05	3.50 ± 0.03	3.44 ± 0.06
Kidneys	4.74 ± 0.03	4.81 ± 0.04	4.69 ± 0.06
Lung	4.23 ± 0.07	4.53 ± 0.06	4.01 ± 0.30
Liver	10.67 ± 0.14	10.90 ± 0.10	10.61 ± 0.09
Spleen	2.56 ± 0.06	2.56 ± 0.07	2.48 ± 0.06
Biochemical parameters
Glucose, mg/dL	119.10 ± 3.27	116.90 ± 3.21	122.30 ± 3.34
Creatinine, mg/dL	0.45 ± 0.02	0.41 ± 0.02	0.45 ± 0.01
Urea, mg/dL	49.50 ± 3.36	53.29 ± 1.11	53.70 ± 3.20
γ-GT, U/L	< 1.0	< 1.0	< 1.0
AST, U/L	202.70 ± 12.73	198.40 ± 18.84	162.10 ± 7.24
ALT, U/L	57.00 ± 3.40	60.57 ± 3.59	65.86 ± 2.79

Vehicle, lansoprazole, or HEEP was administered for 14 d after ulcer induction. Data were collected at the end of treatment. Results are expressed as the means ± standard error of the mean for each group (n = 7-8). Statistical significance was determined using one-way ANOVA followed by Dunnett's test. No significant differences vs vehicle were noted; ALT: Alanine aminotransferase; AST: Aspartate aminotransferase; γ-GT: Gamma-glutamyl transpeptidase. HEEP: Hydroalcoholic extract from the leaves of Eugenia punicifolia.