Colonoscopy attachments for the detection of precancerous lesions during colonoscopy: A review of the literature

Table 1 Add-on devices’ main characteristics

	Cap	Endocuff	Endocuff Vision	Endorings
Manufacturer	Olympus, Centre Valley, Pennsylvania	Arc Medical Leeds, United Kingdom	Norgine Pharmaceuticals Ltd, Uxbridge, United Kingdom	EndoAid, Caesarea, Israel
Launched in market	1993	2011	2016	2015
Short description	Transparent, single-use distal attachment with side hole for draining of fluid	Single-use, soft, radiopaque, 2 cm long cylindrical sleeve with flexible projections arranged in 2 rows of 8, emerging from gaps on the shaft of the device	Single-use, device with single row of 8 flexible 15 mm spikes	Single-use device composed of 2 layers of flexible, soft circular rings, placed on a cylindrical cuff
Material	Thermoplastic elastomer	Core: Non-latex, biocompatible polymer; Projections: thermoplastic elastomer	Latex free, polypropylene	Silicone
Dimensions	Outer diameter ranging from 13.9-16.1 mm according to each type of cap	Finger projections: proximal 8.15 mm, distal 5mm; core length: 23.8 mm; diameter: 16.1, 16.7, 17.2, and 18.5 mm (hairs folded back) and 32.6, 33.1, 33.6, and 34.8 mm (hairs opened out)	Diameter: 16.1, 16.7, 17.2, and 18.5mm (spikes folded back) and 39.07, 39.07, 39.07, and 39.66 mm (spikes opened out)	22-50 mm diameter
Mode of action	Protruding cap manipulates and flattens haustral folds to inspect the mucosa on the proximal side of the fold maintaining optimal field of view	Hinged projections flatten and spread mucosa and folds	Hinged projections flatten and improve visibility behind the colon folds	Sequential rings stretches out the folds of the colon during withdrawal for a clear view
Interfere with view of field	Edge of the hood comes into the vision field of the colonoscope, but lesions can be seen through the transparent wall	No interference of vision	No interference with vision	No interference with vision
Compatible scopes	Adult, pediatric: Ten different sizes, to fit all scopes	Adult, pediatric: 4 color-coded sizes (purple, orange, green and blue) to fit all scopes	Adult, pediatric: 4 color-coded sizes (purple, orange, green and blue) to fit all scopes	Scope Distal End Diameter [mm]; Adult colonoscope 12.8-14.5 mm; Slim Adult colonoscope 11.5-13.0 mm
Advantages	Resection of wider areas; Suction and insufflation of air unaffected	Folds movement provides a dynamic picture - even the smallest polyps can be identified; Centers the scope in the middle of the lumen preventing sudden slip back and “red-out”; Projections allow traction to avoid sudden slippage around turns and flexures, improving scope’s stability; Helps perform EMR	Delivers more tip control without compromising intubation - improving loop management; Early and controlled view of the upstream surface of large folds - no need for repeated intubation; Prevents sudden slip back and red out; Optimizes tip position during therapy and polyp retrieval	Maintains position during loop reduction, decreases slippage, anchoring during endoscopic therapy; Maintains identical depth and breadth of scope's viewing field; Minimal resistance on insertion; Easy ileum intubation
Disadvantages	Interfere with the field of view	Petechial marks on colon; Potential dislodgement; Larger model more effective than smaller; Ileum intubation may be difficult	Potential dislodgement	Ileum intubation may be difficult