Differential expression of mucin 1 and mucin 2 in colorectal cancer

Figure 5 Immunohistochemical illustrations of colorectal carcinoma and control colon with Ki-67 antigen and p53 expression. A: Representative IHC expression of Ki-67 proliferating antigen in the majority of tumor cell nuclei; B: An intense nuclear pattern of Ki-67 expression in focally located tumor cells; C: Representative image of Ki-67 proliferating antigen immunoexpression in the individual basally located nuclei of the goblet cells lining the unaltered intestinal crypts; D: A pronounced p53 nuclear pattern of IHC reaction in glandular structures of CRC; E: Negative IHC reaction for p53 in tumor of other CRC patient; F: Negative IHC reaction for p53 in normal colon. Sections were counterstained with hematoxylin. Objective × 40. IHC: Immunohistochemical; CRC: Colorectal cancer.